Vitamin B12 (Methylcobalamin)

Active form of B12 essential for nerve function, DNA synthesis, and energy production.

VitaminsMorningStrong Evidence

Mechanism of Action

Cofactor for enzymes involved in DNA synthesis, fatty acid metabolism, and nerve cell function. Methylcobalamin is the neurologically active form.

Dosing

Recommended Range
500-2000 mcg
Optimal Timing
Morning
Evidence Level
Strong

Safety Information

Interactions

  • Metformin reduces B12 absorption
  • PPIs may reduce absorption

Contraindications

  • Leber's disease

Comprehensive Information

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