Vitamin B2 (Riboflavin-5-Phosphate)
Active form of Vitamin B2 essential for MTHFR enzyme function and energy production. Critical cofactor for methylation and homocysteine metabolism.
VitaminsMorningStrong Evidence
Mechanism of Action
Riboflavin-5-Phosphate is the active coenzyme form of B2. It serves as a cofactor for the MTHFR enzyme, enabling the conversion of folate to its active form. Essential for energy production via FAD/FMN, supports mitochondrial function, and helps recycle glutathione.
Dosing
- Recommended Range
- 50-100 mg
- Optimal Timing
- Morning
- Evidence Level
- Strong
Safety Information
Interactions
- May enhance effects of other B vitamins
- Works synergistically with folate and B12
Contraindications
- Generally well tolerated
- May cause bright yellow urine (harmless)
Comprehensive Information
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Key Benefits
Natural Food Sources
Optimal Timing & Absorption
Signs of Deficiency
Synergistic Supplements
Practical Tips
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